GEARHART, PATRICIA J.: search on Z-Library

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1

DNA polymerases and somatic hypermutation of immunoglobulin genes

Seki, Mineaki, Gearhart, Patricia J, Wood, Richard D

Journal:

Year:

2005

Language:

english

File:

PDF, 149 KB

english, 2005

2

Generation of Antibody Diversity Before and After Immunization

PATRICIA J. GEARHART, ANN M. LAWLER, NINA S. LEVY, SERGE G. LEBECQUE, URSULA V. MALIPIERO

Journal:

Annals of the New York Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 338 KB

english, 1988

3

A comparative outcome study of frequent, moderate, occasional, and nonattenders of alcoholics anonymous

Charles G. Watson, Martha Hancock, Lee P. Gearhart, Claudia M. Mendez, Patricia Malovrh, Maria Raden

Journal:

Journal of Clinical Psychology

Year:

1997

Language:

english

File:

PDF, 63 KB

english, 1997

4

Social maladjustment indicators in PTSD patients' families of origin

Charles G. Watson, Patricia E. D. Anderson, Lee P. Gearhart

Journal:

Journal of Clinical Psychology

Year:

1996

Language:

english

File:

PDF, 353 KB

english, 1996

5

Dual enigma of somatic hypermutation of immunoglobulin variable genes: targeting and mechanism

David B. Winter, Patricia I. Gearhart

Journal:

Immunological Reviews

Year:

1998

Language:

english

File:

PDF, 4.31 MB

english, 1998

6

Hemangiosarcoma and squamous cell carcinoma in the third eyelid of a horse

Patricia M. Gearhart, Barbara A. Steficek, Simon M. Peteresen-Jones

Journal:

Veterinary Ophthalmology

Year:

2007

Language:

english

File:

PDF, 298 KB

english, 2007

7

Immunology: The roots of antibody diversity

Gearhart, Patricia J.

Journal:

Year:

2002

Language:

english

File:

PDF, 61 KB

english, 2002

8

Posttraumatic Stress Disorder (PTSD) Symptoms in PTSD Patientsʼ Families of Origin

WATSON, CHARLES G., ANDERSON, PATRICIA E. D., GEARHART, LEE P.

Journal:

Journal of Nervous & Mental Disease

Year:

1995

File:

PDF, 547 KB

1995

9

10.1038/ni1101-984

Gearhart, Patricia J., Zeng, Xianmin

Journal:

Nature Immunology

Year:

2001

Language:

english

File:

PDF, 21 KB

english, 2001

10

Activation-induced deaminase-mediated class switch recombination is blocked by anti-IgM signaling in a phosphatidylinositol 3-kinase-dependent fashion

Lynn M. Heltemes-Harris, Patricia J. Gearhart, Paritosh Ghosh, Dan L. Longo

Journal:

Molecular Immunology

Year:

2008

Language:

english

File:

PDF, 870 KB

english, 2008

11

Refining the Neuberger model: Uracil processing by activated B cells

Maul, Robert W., Gearhart, Patricia J.

Journal:

European Journal of Immunology

Year:

2014

Language:

english

File:

PDF, 326 KB

english, 2014

12

Improvement of Visual Performance With Intravitreal Administration of 9-cis-Retinal in Rpe65-Mutant Dogs

Gearhart, Patricia M.

Journal:

Archives of Ophthalmology

Year:

2010

Language:

english

File:

PDF, 1015 KB

english, 2010

13

DNA Deamination in Immunity, Virology and Cancer || Preface

Patricia J. Gearhart, Tomas Lindahl and Michael S. Neuberger

Journal:

Philosophical Transactions Biological Sciences

Year:

2009

Language:

english

File:

PDF, 426 KB

english, 2009

14

Naive B Cells with High-Avidity Germline-Encoded Antigen Receptors Produce Persistent IgM + and Transient IgG + Memory B Cells

Pape, Kathryn A., Maul, Robert W., Dileepan, Thamotharampillai, Paustian, Amanda Schmidt, Gearhart, Patricia J., Jenkins, Marc K.

Journal:

Year:

2018

Language:

english

File:

PDF, 3.47 MB

english, 2018

15

Does DNA repair occur during somatic hypermutation?

Saribasak, Huseyin, Gearhart, Patricia J.

Journal:

Seminars in Immunology

Year:

2012

Language:

english

File:

PDF, 388 KB

english, 2012

16

Heterocyclic studies. 38. Rearrangement of a 9-acyl-1,9-diazabicyclo[4.2.1]nonadienone to a pyrrolo[1,2-b]pyridazinone

Moore, James A., Gearhart, Richard C., Rothenberger, Otis S., Thorstenson, Patricia C., Wood, Robert H.

Journal:

Journal of Organic Chemistry

Year:

1972

Language:

english

File:

PDF, 703 KB

english, 1972

17

The Reign of Antibodies: A Celebration of and Tribute to Michael Potter and His Homogeneous Immunoglobulin Workshops

Gearhart, Patricia J., Mock, Beverly A., Casellas, Rafael, Cancro, Michael P.

Journal:

The Journal of Immunology

Year:

2018

Language:

english

File:

PDF, 977 KB

english, 2018

18

Controlling somatic hypermutation in immunoglobulin variable and switch regions

Robert W. Maul, Patricia J. Gearhart

Journal:

Immunologic Research

Year:

2010

Language:

english

File:

PDF, 332 KB

english, 2010

19

Exceptional Antibodies Produced by Successive Immunizations

Gearhart, Patricia J., Castiblanco, Diana P., Russell Knode, Lisa M.

Journal:

Year:

2015

Language:

english

File:

PDF, 541 KB

english, 2015

20

Characterization of an aFGF Gene Expression Vector with Therapeutic Potential

Marcin T. Tchorzewski, Mark D. Duncan, Petra Nass, Faisal G. Qureshi, Patricia J. Gearhart, Richard Winchurch, John W. Harmon

Journal:

Journal of Surgical Research

Year:

1998

Language:

english

File:

PDF, 247 KB

english, 1998

21

Topoisomerase I deficiency causes RNA polymerase II accumulation and increases AID abundance in immunoglobulin variable genes

Maul, Robert W., Saribasak, Huseyin, Cao, Zheng, Gearhart, Patricia J.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.34 MB

english, 2015

22

Antibody diversification caused by disrupted mismatch repair and promiscuous DNA polymerases

Zanotti, Kimberly J., Gearhart, Patricia J.

Journal:

Year:

2016

Language:

english

File:

PDF, 380 KB

english, 2016

23

Hypermutation in Antibody Genes || Preface

Richard D. Wood, Patricia J. Gearhart and Michael S. Neuberger

Journal:

Philosophical Transactions Biological Sciences

Year:

2001

Language:

english

File:

PDF, 285 KB

english, 2001

24

Reciprocal homologous recombination in or near antibody VDJ genes

Asad Umar, Patricia J. Gearhart

Journal:

European Journal of Immunology

Year:

1995

Language:

english

File:

PDF, 1.04 MB

english, 1995

25

Nucleotide excision repair in an immunoglobulin variable gene is less efficient than in a housekeeping gene

Rudaina H. Alrefai, David B. Winter, Vilhelm A. Bohr, Patricia J. Gearhart

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 382 KB

english, 2007

26

A Novel Method for Objective Vision Testing in Canine Models of Inherited Retinal Disease

Gearhart, Patricia M., Gearhart, Chris C., Petersen-Jones, Simon M.

Journal:

Investigative Ophthalmology & Visual Science

Year:

2008

Language:

english

File:

PDF, 284 KB

english, 2008

27

[Part 1: Biological Sciences] || Clusters of Point Mutations are Found Exclusively around Rearranged Antibody Variable Genes

Patricia J. Gearhart and Daniel F. Bogenhagen

Journal:

Proceedings of the National Academy of Sciences

Year:

1983

Language:

english

File:

PDF, 857 KB

english, 1983

28

Production of Antibodies of Identical Idiotype but Diverse Immunoglobulin Classes by Cells Derived from a Single Stimulated B Cell

Patricia J. Gearhart, Nolan H. Sigal and Norman R. Klinman

Journal:

Proceedings of the National Academy of Sciences

Year:

1975

Language:

english

File:

PDF, 828 KB

english, 1975

29

Hepatocyte Nuclear Factor–1 β Regulates Urinary Concentration and Response to Hypertonicity

Aboudehen, Karam, Noureddine, Lama, Cobo-Stark, Patricia, Avdulov, Svetlana, Farahani, Shayan, Gearhart, Micah D., Bichet, Daniel G., Pontoglio, Marco, Patel, Vishal, Igarashi, Peter

Journal:

Journal of the American Society of Nephrology

Year:

2017

Language:

english

File:

PDF, 2.59 MB

english, 2017

30

Early postnatal development of central corneal thickness in dogs

Fabiano Montiani-Ferreira, Simon Petersen-Jones, Nicholas Cassotis, David T. Ramsey, Patricia Gearhart, Fernando Cardoso

Journal:

Veterinary Ophthalmology

Year:

2003

Language:

english

File:

PDF, 206 KB

english, 2003

31

From Influenza Virus Infections to Lupus: Synchronous Estrogen Receptor Î± and RNA Polymerase II Binding Within the Immunoglobulin Heavy Chain Locus

Jones, Bart G., Sealy, Robert E., Penkert, Rhiannon R., Surman, Sherri L., Birshtein, Barbara K., Xu, Beisi, Neale, Geoffrey, Maul, Robert W., Gearhart, Patricia J., Hurwitz, Julia L.

Journal:

Viral Immunology

Year:

2020

Language:

english

File:

PDF, 472 KB

english, 2020

32

EMERGING LINKS BETWEEN HYPERMUTATION OF ANTIBODY GENES AND DNA POLYMERASES

Gearhart, Patricia J., Wood, Richard D.

Journal:

Nature Reviews Immunology

Year:

2001

Language:

english

File:

PDF, 263 KB

english, 2001

33

Hotspots for Vitamin–Steroid–Thyroid Hormone Response Elements Within Switch Regions of Immunoglobulin Heavy Chain Loci Predict a Direct Influence of Vitamins and Hormones on B Cell Class Switch Recombination

Hurwitz, Julia L., Penkert, Rhiannon R., Xu, Beisi, Fan, Yiping, Partridge, Janet F., Maul, Robert W., Gearhart, Patricia J.

Journal:

Viral Immunology

Year:

2016

Language:

english

File:

PDF, 803 KB

english, 2016

34

Binding of estrogen receptors to switch sites and regulatory elements in the immunoglobulin heavy chain locus of activated B cells suggests a direct influence of estrogen on antibody expression

Jones, Bart G., Penkert, Rhiannon R., Xu, Beisi, Fan, Yiping, Neale, Geoff, Gearhart, Patricia J., Hurwitz, Julia L.

Journal:

Molecular Immunology

Year:

2016

Language:

english

File:

PDF, 786 KB

english, 2016

35

What Targets Somatic Hypermutation to the Immunoglobulin Loci?

Heltzel, Justin M.H., Gearhart, Patricia J.

Journal:

Viral Immunology

Year:

2019

Language:

english

File:

PDF, 211 KB

english, 2019

36

Non-sequential expression of multiple immunoglobulin classes by isolated B-cell clones

GEARHART, PATRICIA J.

Journal:

Year:

1977

File:

PDF, 267 KB

1977

37

Differential expression of DNA polymerase ϵ in resting and activated B lymphocytes is consistent with an in vivo role in replication and not repair

David B. Winter, Quy H. Phung, Richard D. Wood, Patricia J. Gearhart

Journal:

Molecular Immunology

Year:

2000

Language:

english

File:

PDF, 249 KB

english, 2000

38

Defective Repair of Uracil Causes Telomere Defects in Mouse Hematopoietic Cells

Vallabhaneni, Haritha, Zhou, Fang, Maul, Robert W., Sarkar, Jaya, Yin, Jinhu, Lei, Ming, Harrington, Lea, Gearhart, Patricia J., Liu, Yie

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 2.99 MB

english, 2015

39

Matters of life and death: How estrogen and estrogen receptor binding to the immunoglobulin heavy chain locus may influence outcomes of infection, allergy, and autoimmune disease

Jones, Bart G., Penkert, Rhiannon R., Surman, Sherri L., Sealy, Robert E., Pelletier, Stephane, Xu, Beisi, Neale, Geoff, Maul, Robert W., Gearhart, Patricia J., Hurwitz, J.L.

Journal:

Cellular Immunology

Year:

2019

File:

PDF, 661 KB

2019

40

Idiotype-specific neonatal suppression of phosphorylcholine-responsive B cells

R. S. Accolla, Patricia J. Gearhart, N. H. Sigal, M. P. Cancro, N. R. Klinman

Journal:

European Journal of Immunology

Year:

1977

Language:

english

File:

PDF, 677 KB

english, 1977

41

B cells pay a price

Gearhart, Patricia J

Journal:

Year:

2003

Language:

english

File:

PDF, 86 KB

english, 2003

42

Impact of Age on Hypermutation of Immunoglobulin Variable Genes in Humans

Karli Rosner, David B. Winter, Cynthia Kasmer, Gunhild Lange Skovgaard, Robert E. Tarone, Vilhelm A. Bohr, Patricia J. Gearhart

Journal:

Journal of Clinical Immunology

Year:

2001

Language:

english

File:

PDF, 497 KB

english, 2001

43

Insertion of 2 kb of bacteriophage DNA between an immunoglobulin promoter and leader exon stops somatic hypermutation in a κ transgene

David B. Winter, Nasreen Sattar, Jia-Jia Mai, Patricia J. Gearhart

Journal:

Molecular Immunology

Year:

1997

Language:

english

File:

PDF, 999 KB

english, 1997

44

Altered Spectra of Hypermutation in Antibodies from Mice Deficient for the DNA Mismatch Repair Protein PMS2

David B. Winter, Quy H. Phung, Asad Umar, Sean M. Baker, Robert E. Tarone, Kiyoji Tanaka, R. Michael Liskay, Thomas A. Kunkel, Vilhelm A. Bohr and Patricia J. Gearhart

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1000 KB

english, 1998

45

Somatic hypermutation: subverted DNA repair

Stella A Martomo, Patricia J Gearhart

Journal:

Current Opinion in Immunology

Year:

2006

Language:

english

File:

PDF, 255 KB

english, 2006

46

Esophagogastric adenocarcinoma in an E1A/E1B transgenic model involves p53 disruption

Mark D. Duncan, Tarik Tihan, David M. Donovan, Quy H. Phung, Dan L. Rowley, John W. Harmon, Patricia J. Gearhart, Kimberly L.K. Duncan

Journal:

Journal of Gastrointestinal Surgery

Year:

2000

Language:

english

File:

PDF, 881 KB

english, 2000

47

Linkage of two pseudogenes from Vκ1 and Vκ9 murine immunoglobulin families

Ann M. Lawler, Asad Umar, Patricia J. Gearhart

Journal:

Molecular Immunology

Year:

1992

Language:

english

File:

PDF, 991 KB

english, 1992

48

Mutation in a Reporter Gene Depends on Proximity to and Transcription of Immunoglobulin Variable Transgenes

Asad Umar, Peter A. Schweitzer, Nina S. Levy, John D. Gearhart and Patricia J. Gearhart

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.00 MB

english, 1991

49

DNA Deamination in Immunity, Virology and Cancer || Hijacked DNA Repair Proteins and Unchained DNA Polymerases

Huseyin Saribasak, Deepa Rajagopal, Robert W. Maul and Patricia J. Gearhart

Journal:

Philosophical Transactions Biological Sciences

Year:

2009

Language:

english

File:

PDF, 1.23 MB

english, 2009

50

Regulating Antibody Diversity: Taming a Mutagen

Patricia J. Gearhart, Ranjan Sen

Journal:

Year:

2008

Language:

english

File:

PDF, 120 KB

english, 2008

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